I have been using CFEclipse 1.3.1.5 and Eclipse 3.3 on my Vista Laptop for some time now, but recently had problems when I went to upgrade my desktop setup to match. I kept getting a variety of errors, including "problems opening perspective 'org.cfeclipse.cfml.perspective.CFML'". This was uber-frustrating since the very same setup was working on my laptop. After a bit of Googleing around I realized what was wrong... I was using an old JRE on my desktop! If you run into this same problem, here's how to fix it:

1. Download and install/unpack the most recent JDK/JRE (1.6.0_02 in my case) from Sun
2. Add/Change the JRE in your OS Path
3. Restart for good measure
4. Done!

Note: You can also start Eclipse with a specific JVM (without changing your OS Path) by specifying it on the command line. Look here for more information on starting Eclipse on the command line.